: Researchers often use MCODE alongside other tools like cytoHubba to identify "hub genes"—nodes with high connectivity that are likely critical for the network's stability.
Unlike simpler clustering methods that only look at node connectivity, MCODE uses a three-stage automated algorithm to score and isolate molecular complexes based on network topology: mcode cytoscape
: It breaks down massive "hairball" networks into manageable subnetworks that represent specific biological functions, such as cell cycle regulation or metabolic pathways. : Researchers often use MCODE alongside other tools