Mastercam is developed exclusively for the Microsoft Windows operating system. If you download the installer from the official Mastercam website, it will be an executable file (.exe) that cannot run on macOS without intervention.
For those seeking an open-source solution, FreeCAD offers a "Path Workbench" for basic CAM functionality. System Requirements for Running Mastercam on Mac mastercam for mac
A: For basic CAM, yes. For advanced multiaxis and machine simulation, no. Mastercam is developed exclusively for the Microsoft Windows
If you intend to run Mastercam on a Mac via virtualization, you need higher specs than the average user to compensate for the overhead of the virtual machine. mastercam for mac