That quirk is non-negotiable. Without it, you’ll pull your hair out. With it, it just works.

Start JACK with:

A common fix for audio dropouts on certain Linux kernels involves enabling "implicit feedback" for the snd-usb-audio module. Guitarix & Behringer UMC202HD - LinuxMusicians

Once the quirk is active:

sudo modprobe -r snd_usb_audio sudo modprobe snd_usb_audio quirk_alias=041e:3f19:0x0b92

More recently, PipeWire has emerged as a unifying layer, attempting to merge the low-latency goals of JACK with the consumer ease-of-use of PulseAudio. The UMC202HD shines in a PipeWire environment. Because PipeWire creates a graph that can dynamically reconfigure the hardware parameters, the interface can switch sample rates on the fly (a feature known as "auto-profile switching"). For example, listening to 44.1kHz music on Spotify and then switching to a 96kHz Ardour session is handled transparently by PipeWire, which instructs ALSA to reconfigure the UMC202HD. This level of integration makes the hardware feel "native" to the OS, surpassing the user experience of many proprietary drivers on Windows that require manual rate switching in a control panel.