Origin Seems To Be Running No Communication With Orange Is Possible [work] Now

This is the #1 fix. Even if Origin isn't visible, it may be running in the background.

Your security software may be blocking the "Orange" handshake. This is the #1 fix

In the year 2154, humanity had colonized several planets in the distant reaches of the galaxy. The United Earth Government (UEG) had established a program called ORIGIN, a vast network of interconnected artificial intelligences designed to manage and govern the colonies. ORIGIN was the brainchild of the brilliant and reclusive scientist, Dr. Elara Vex. This is the #1 fix

If the error disappears, add EA/Origin as an exception in your antivirus. This is the #1 fix